The One Eyed Buffalo Brewing Company
The One Eyed Buffalo Brewing Company
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One Eyed Buffalo Brewing Company

One Eyed Buffalo Brewing CompanyOne Eyed Buffalo Brewing CompanyOne Eyed Buffalo Brewing Company
Logo for One Eyed Buffalo Brewing Company in Thermopolis, Wyoming.

The OEB Story

Since its inception in 2015, the One Eyed Buffalo Brewing Company has been a staple in Thermopolis, Wyoming. In 2024, it moved to a larger location across the street, continuing to serve the community with high-quality food, local beer and liquor, and incredible service at the One Eyed Buffalo Thermopolis.

Craft beers and growlers from One Eyed Buffalo Brewing Company on a wooden table.

Crowlers & Growlers

At One Eyed Buffalo Brewing Company in Thermopolis, WY, crowlers and growlers are the only way to purchase our beer packaged! They make fantastic gifts, memorable keepsakes, or a convenient way to take your favorite brews with you. Plus, feel free to bring in your own growler for a refill when you visit One Eyed Buffalo in Thermopolis, Wyoming!

All-you-can-eat prime rib, crab, and seafood buffet every Thursday night for $59.99.

Prime, Crab, and Seafood Buffet

Join us every Thursday evening at 5pm at the One Eyed Buffalo Brewing Company in Thermopolis, WY for our all-you-can-eat buffet. Enjoy our house prime rib, snow crab, black mussels, crawfish, shrimp, and clams for just $59.99 per person! You can't beat this amazing deal at One Eyed Buffalo Thermopolis, Wyoming!

About One Eyed Buffalo

Grilled lobster tails with asparagus and broccoli on a dark plate.

Our Kitchen

Events & Parties

Our Kitchen

At the One Eyed Buffalo Brewing Company in Thermopolis, we are constantly pushing out new specials, fresh seafood, perfectly cooked steaks, and homemade comfort food that offers a fine dining experience. Stop by the One Eyed Buffalo in Thermopolis, WY, to try a fresh char-broiled half pound beef or bison burger, buttery twin lobster tails, or our delicious salad bar!

A frothy beer in a One Eyed Buffalo Brewing Company glass at a bar.

Our Brews

Events & Parties

Our Kitchen

At One Eyed Buffalo Brewing Company, located in Thermopolis, WY, we are dedicated to brewing exceptional beers that showcase bold, rich flavors inspired by our local community. Our commitment to quality and craftsmanship is evident in every pint we pour at One Eyed Buffalo Thermopolis in Wyoming.

A creamy chocolate cocktail garnished with cherries on a pink sword pick.

Events & Parties

Events & Parties

Events & Parties

Host your next company event or birthday party at the One Eyed Buffalo Brewing Company in Thermopolis, WY. For more information, click the link below, call 307-864-3555, or email us at: oeb@oebbrewingco.com.

Learn More

Special Events

Ryan Littleeagle's Wyoming tour dates and venues from February 25 to March 1st.
John Gerrells Benefit Cookie Jar & Basket Auction on March 20, 2026.

Contact Us

Open 7 Days a Week!

One Eyed Buffalo Brewing Company

535 Broadway Street, Thermopolis, Wyoming 82443, United States

307-864-3555

Hours

Open today

11:00 am – 09:00 pm

Copyright © 2026 One Eyed Buffalo - All Rights Reserved.

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